Drug Resistance
R-Biopharm Australia provides advanced antimicrobial resistance testing solutions for the rapid, reliable detection of clinically significant antibiotic resistance genes. Using highly sensitive multiplex PCR technology, our molecular diagnostic panels enable comprehensive antimicrobial resistance PCR testing, delivering same-day identification of critical resistance markers including carbapenemases, extended-spectrum β-lactamases (ESBLs), methicillin resistance (mecA) and vancomycin resistance genes. By providing fast, accurate resistance gene detection, our assays support informed antimicrobial stewardship, improve infection prevention and control, and enable timely treatment decisions. Combined with automated extraction solutions and integrated PCR workflows, our antimicrobial resistance diagnostics provide an efficient end-to-end solution for modern hospital pathology and clinical microbiology laboratories.
Rapid Detection of Antimicrobial Resistance
Antimicrobial resistance continues to present significant challenges for healthcare systems worldwide, making rapid and accurate detection of resistance markers essential for effective patient care and infection control. R-Biopharm Australia’s multiplex PCR solutions enable clinical laboratories to identify clinically important antimicrobial resistance genes quickly and reliably, supporting informed treatment decisions and antimicrobial stewardship programs.
Designed for modern molecular diagnostic laboratories, our assays detect a broad range of resistance mechanisms, including carbapenemases, extended-spectrum β-lactamases (ESBLs) and methicillin resistance markers. By delivering comprehensive molecular results with fast turnaround times, our solutions help laboratories streamline workflows, improve diagnostic confidence and support better patient outcomes.
Drug Resistance PCR Testing Portfolio
CRE & ESBL
A selection of clinically relevant panels that detect resistance markers of Enterobacteriaceae which commonly cause infections within healthcare and community settings. High spread levels of extended-spectrum β-lactamases (ESBL) make testing for resistance increasingly necessary, since carbapenems are one of the few remaining antibiotics that can combat ESBL-producing pathogens. Although mostly effective, resistance enzymes such as carbapenemases confer antibiotic resistance, posing a serious public health concern.
These panels detect a representative selection of simple β-lactamases, extended-spectrum β-lactamases (ESBL) and carbapenemases. The selection of targets in each panel reflects the relevance of ESBL or CRE in different geographical regions.
Resistance Genes
Ambler Class A Carbapenemases
- CTX-M Groups 1 and 9
- KPC
- pan-SHV
- pan-TEM
- VEB
Ambler Class B Metallo-β-Lactamases
- pan-IMP
- NDM
- VIM
Ambler Class C β-Lactamases
- CMY-1
- pan-CMY
- DHA-1
Ambler Class D β-Lactamases
- OXA-1
- OXA-48-like
Ordering Informatio–
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 21093S | RIDA®Plex ESBL 16 well Step 1 | 12 x 8-well Strips | 96 |
| 21093P | RIDA®Plex ESBL 16 well Step 2 | 12 x 384-well Plates | 288 |
| 40231 | RIDA®Plex L DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Resistance Genes
Ambler Class A Carbapenemases
- CTX-M Groups 1 and 9
- GES
- KPC
- IMI
- SME
Ambler Class B Metallo-β-Lactamases
- pan-IMP
- NDM-1
- pan-VIM
Ambler Class C β-Lactamases
- pan-CMY
Ambler Class D β-Lactamases
- OXA-23-like
- OXA-48-like
- OXA-51-like
- OXA-58
Ordering Information
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 21098S | RIDA®Plex CRE 16 well Step 1 | 12 x 8-well Strips | 96 |
| 21098P | RIDA®Plex CRE 16 well Step 2 | 12 x 384-well Plates | 288 |
| 40231 | RIDA®Plex L DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Resistance Genes
Ambler Class A Carbapenemases
- FRI
- GES
- IMI
- KPC
- SME
Ambler Class B Metallo-β-Lactamases
- GIM
- IMP-8
- IMP-14
- pan-IMP
- NDM-1
- pan-VIM
- SIM
- SPM
Ambler Class D β-Lactamases
- OXA-48-like
Other
- Mobilised colistin resistance gene (mcr-1)
Ordering Information
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 21099S | RIDA®Plex CRE EU 16 well Step 1 | 12 x 8-well Strips | 96 |
| 21099P | RIDA®Plex CRE EU 16 well Step 2 | 12 x 384-well Plates | 288 |
| 40231 | RIDA®Plex L DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Resistance Genes
Ambler Class A Carbapenemases
- FRI
- GES
- IMI
- KPC
- PER
- SME
- VEB
Ambler Class B Metallo-β-Lactamases
- DIM
- GIM
- IMP-8
- IMP-14
- pan-IMP
- NDM
- SIM
- SPM
- VIM
Ambler Class D β-Lactamases
- OXA-23-like
- OXA 24/40
- OXA-48-like
- OXA-51-like
- OXA-58
Other
- D179Y
- Mobilised colistin resistance gene (mcr-1)
Ordering Information
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 81098S | RIDA®Plex CRE Reference 24 well Step 1 | 12 x 8-well Strips | 96 |
| 81098P | RIDA®Plex CRE Reference 24 well Step 2 | 12 x 384-well Plates | 192 |
| 40231 | RIDA®Plex L DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Gram Positive Resistance
A select collection of panels of gram-positive pathogens that are a common cause of wound, urinary tract and nosocomial infections, in addition to their antimicrobial resistance markers.
Bacteria
- Enterococcus faecalis
- Enterococcus faecium
- Staphylococcus aureus
Resistance Genes
- Methicillin resistance gene mecA in S. aureus
- Vancomycin resistance genes vanA and vanB in Enterococcus spp.
Ordering Information
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 21340S | RIDA®Plex Staphylococcus and VRE 8 well Step 1 | 12 x 8-well Strips | 96 |
| 21340P | RIDA®Plex Staphylococcus and VRE 8 well Step 2 | 12 x 384-well Plates | 288 |
| 40241 | RIDA®Plex S DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Bacteria
- Staphylococcus spp.
- Staphylococcus aureus
- Staphylococcus epidermidis
Resistance Genes
- Methicillin resistance gene mecA in S. aureus, including Mec LGA251
- Cytotoxin Pantun-Valentine Leukocidin (PVL) in S. aureus
Ordering Information
| Ref | Description | Pack Size | Tests |
|---|---|---|---|
| 21341S | RIDA®Plex Staphylococcus Typing 8 well Step 1 | 12 x 8-well Strips | 96 |
| 21341P | RIDA®Plex Staphylococcus Typing 8 well Step 2 | 12 x 384-well Plates | 288 |
| 40241 | RIDA®Plex S DNA Cassette | 10 Cassettes | – |
| 91151 | RIDA®Plex Positive Control Bacteria and Resistances | 10 x 2mL Tubes | – |
Supporting Clinical Laboratories
Our antimicrobial resistance testing solutions are designed for hospital pathology laboratories, clinical microbiology laboratories and reference laboratories requiring rapid identification of clinically significant antimicrobial resistance genes. Using advanced multiplex PCR technology, our assays simultaneously detect a comprehensive range of resistance mechanisms from a single sample, enabling faster diagnosis than conventional susceptibility testing while supporting effective infection prevention and antimicrobial stewardship programmes.
Supporting the detection of carbapenemases, extended-spectrum β-lactamases (ESBLs), methicillin resistance (mecA), vancomycin resistance (vanA/vanB) and other important resistance markers, our molecular diagnostic solutions improve laboratory efficiency, increase diagnostic confidence and provide clinicians with fast, actionable results to support appropriate antimicrobial therapy.
Explore Our Technology
R-Biopharm Australia’s antimicrobial resistance testing portfolio combines automated nucleic acid extraction (RIDA®Xtract 24 & RIDA®Xtract 96), advanced multiplex PCR instrumentation (RIDA®Xplore & RIDA®Jump) and integrated molecular diagnostic workflows to deliver rapid detection of clinically significant resistance genes. Designed for hospital pathology and clinical microbiology laboratories, these solutions reduce hands-on time, improve throughput and provide fast, reliable molecular results that support antimicrobial stewardship and infection control programmes.
RIDA®Plex IVD panels are intended for in vitro diagnostics use by authorised clinical testing laboratories in Australia, New Zealand, Great Britain, and the European Economic Area, and are included on the Australian Register of Therapeutic Goods (ARTG), the MHRA database (REF: 10541) and compliant with the European IVD Directive 98/79/EC. In the USA: For Research Use Only (RUO). For Research Use Only (RUO), not for use In diagnostic procedures. RIDA®Plex RUO panels are for Research Use Only in any jurisdiction.
